MSI1
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
Full Name
Musashi RNA Binding Protein 1
Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U1-3AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Biological Process
Epithelial cell differentiation Source: Ensembl
Nervous system development Source: ProtInc
Response to hormone Source: Ensembl
Nervous system development Source: ProtInc
Response to hormone Source: Ensembl
Cellular Location
Cytoplasm
Nucleus
Nucleus
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Anti-MSI1 antibodies
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CompareTarget: MSI1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Chicken
Clone: EP1302
Application*: F, IC, IF, C, P, IP, WB
Target: MSI1
Sensitivity: 0.007 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Msi1
Sensitivity: 0.0052 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: MSI1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT898
Application*: WB, F, E
Target: MSI1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2667
Application*: WB, F
Target: MSI1
Specificity: Human
Target: MSI1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A1190
Application*: WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A1189
Application*: WB
Target: MSI1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D46A8
Application*: WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F2
Application*: WB, E
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1B11
Application*: WB, E
Target: MSI1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2637
Application*: F, IC, IH, IP, WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-2636
Application*: WB, F, IH, IF, P
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBFYM-2635
Application*: WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2634
Application*: E, IF, P, WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-2633
Application*: E, P, WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2632
Application*: E, P, WB
Target: MSI1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-2631
Application*: WB
Target: MSI1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2630
Application*: WB, P, IF, IP, F
Target: MSI1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBFYM-0386
Application*: WB, BI, F
Target: MSI1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0282
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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