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MSI1

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]

Full Name

Musashi RNA Binding Protein 1

Function

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U1-3AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

Biological Process

Epithelial cell differentiation Source: Ensembl
Nervous system development Source: ProtInc
Response to hormone Source: Ensembl

Cellular Location

Cytoplasm
Nucleus

Anti-MSI1 antibodies

Rabbit Anti-MSI1 Monoclonal Antibody (EP1302) (CBMAB-1399-YC)

SDS

Target: MSI1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Chicken

Clone: EP1302

Application*: F, IC, IF, C, P, IP, WB

Rabbit Anti-MSI1 (N-terminus) Recombinant Antibody (CBFYM-2637) (CBMAB-M2826-FY)

SDS

Target: MSI1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-2637

Application*: F, IC, IH, IP, WB

Mouse Anti-MSI1 Recombinant Antibody (CBFYM-2636) (CBMAB-M2825-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYM-2636

Application*: WB, F, IH, IF, P

Mouse Anti-MSI1 Recombinant Antibody (CBFYM-2635) (CBMAB-M2824-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse, Rat

Clone: CBFYM-2635

Application*: WB

Mouse Anti-MSI1 (AA 1-87) Recombinant Antibody (CBFYM-2634) (CBMAB-M2823-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-2634

Application*: E, IF, P, WB

Mouse Anti-MSI1 (AA 1-87) Recombinant Antibody (CBFYM-2633) (CBMAB-M2822-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYM-2633

Application*: E, P, WB

Mouse Anti-MSI1 (AA 190-273) Recombinant Antibody (CBFYM-2632) (CBMAB-M2821-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-2632

Application*: E, P, WB

Mouse Anti-MSI1 (AA 1-362) Recombinant Antibody (CBFYM-2631) (CBMAB-M2820-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYM-2631

Application*: WB

Rabbit Anti-MSI1 Recombinant Antibody (CBFYM-2630) (CBMAB-M2819-FY)

SDS

Target: MSI1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-2630

Application*: WB, P, IF, IP, F

Mouse Anti-MSI1 Recombinant Antibody (CBFYM-0386) (CBMAB-M0479-FY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Rat

Clone: CBFYM-0386

Application*: WB, BI, F

Rabbit Anti-MSI1 Recombinant Antibody (CBFYM-0282) (CBMAB-M0347-FY)

SDS

Target: MSI1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-0282

Application*: WB

Mouse Anti-MSI1 Recombinant Antibody (A1190) (CBMAB-AP12299LY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: A1190

Application*: WB

Mouse Anti-MSI1 Recombinant Antibody (A1189) (CBMAB-AP4937LY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: A1189

Application*: WB

Rabbit Anti-MSI1 Recombinant Antibody (D46A8) (CBMAB-CP1613-LY)

SDS

Target: MSI1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: D46A8

Application*: WB

Mouse Anti-MSI1 Recombinant Antibody (3F2) (CBMAB-A5612-LY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3F2

Application*: WB, E

Mouse Anti-MSI1 Recombinant Antibody (1B11) (CBMAB-A5610-LY)

SDS

Target: MSI1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1B11

Application*: WB, E

MSI1 Matched Antibody Pair (757) (APMAB-757LY)

SDS

Target: MSI1

Specificity: Human

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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