MSMB

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
Full Name
microseminoprotein, beta-
Cellular Location
Secreted
Note: Sperm surface.
Involvement in disease
Prostate cancer, hereditary, 13 (HPC13):
A condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
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Anti-MSMB antibodies

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Mouse Anti-MSMB Recombinant Antibody (3B11) (CBMAB-A5625-LY)

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Target: MSMB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3B11
Application*: WB, E
Datasheet SDS

Mouse Anti-MSMB Recombinant Antibody (YPSP-1) (CBMAB-P0513-YC)

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Target: MSMB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: YPSP-1
Application*: WB, E, IC, IF
Datasheet SDS

Mouse Anti-MSMB Recombinant Antibody (CBFYM-2653) (CBMAB-M2842-FY)

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Target: MSMB
Host: Mouse
Specificity: Human
Clone: CBFYM-2653
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-MSMB Recombinant Antibody (CBFYM-0737) (CBMAB-M0879-FY)

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Target: MSMB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0737
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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