MUC17
The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
Full Name
MUC17
Function
Probably plays a role in maintaining homeostasis on mucosal surfaces.
Biological Process
Cellular homeostasis Source: UniProtKB
Cellular Location
Isoform 1:
Plasma membrane
Cell membrane
Isoform 2:
Secreted
Plasma membrane
Cell membrane
Plasma membrane
Cell membrane
Isoform 2:
Secreted
Plasma membrane
Cell membrane
Topology
Extracellular: 26-4393
Helical: 4394-4414
Cytoplasmic: 4415-4493
Helical: 4394-4414
Cytoplasmic: 4415-4493
PTM
Probably cleaved within the SEA domain.
N-glycosylated. Contains high mannose and complex-type glycans. The forms containing the complex type glycans localize to the cell surface. Not O-glycosylated.
N-glycosylated. Contains high mannose and complex-type glycans. The forms containing the complex type glycans localize to the cell surface. Not O-glycosylated.
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Anti-MUC17 antibodies
+ Filters

Target: MUC17
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 9BA7
Application*: E, WB
Target: MUC17
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: NCRC74
Application*: E
Target: MUC17
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1143/B7
Application*: E, IH
Target: MUC17
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1175
Application*: E, F, IH
Target: MUC17
Host: Mouse
Specificity: Human
Clone: CBFYM-2798
Application*: WB, IC, P, C, E
Target: MUC17
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 9BA6
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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