N2 (H3N2)

Neuraminidase catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
Full Name
Neuraminidase subtype 2

Anti-N2 (H3N2) antibodies

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Mouse Anti-N2 (H3N2) Recombinant Antibody (218C11) (CBMAB-YT465LY)

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Target: N2 (H3N2)
Host: Mouse
Antibody Isotype: IgG1
Specificity: Avian Influenza Virus
Clone: 218C11
Application*: WB, ELISA, IP, IF
Datasheet SDS

Mouse Anti-N2 (H3N2) Recombinant Antibody (117H10) (CBMAB-YT464LY)

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Target: N2 (H3N2)
Host: Mouse
Antibody Isotype: IgG1
Specificity: Avian Influenza Virus
Clone: 117H10
Application*: WB, ELISA, IP, IF
Datasheet SDS

Mouse Anti-N2 (H3N2) Recombinant Antibody (10A9) (CBMAB-YT463LY)

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Target: N2 (H3N2)
Host: Mouse
Antibody Isotype: IgG1
Specificity: Avian Influenza Virus
Clone: 10A9
Application*: WB, ELISA, IP, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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