OGFOD1
OGFOD1 (2-Oxoglutarate And Iron Dependent Oxygenase Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
Full Name
2-Oxoglutarate And Iron Dependent Oxygenase Domain Containing 1
Function
Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation.
Biological Process
Cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-proline hydroxylationManual Assertion Based On ExperimentIDA:CACAO
Protein hydroxylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of translational terminationManual Assertion Based On ExperimentIMP:UniProtKB
Stress granule assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-proline hydroxylationManual Assertion Based On ExperimentIDA:CACAO
Protein hydroxylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of translational terminationManual Assertion Based On ExperimentIMP:UniProtKB
Stress granule assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Isoform 1
Cytoplasm
Nucleus
Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.
Isoform 2
Cytoplasm
Cytoplasm
Nucleus
Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.
Isoform 2
Cytoplasm
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Anti-OGFOD1 antibodies
+ Filters

Target: OGFOD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G6
Application*: F, WB
Target: OGFOD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F4
Application*: F, P, WB
Target: OGFOD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 1D9
Application*: WB, F, IF, IH, P
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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