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OGFOD1

OGFOD1 (2-Oxoglutarate And Iron Dependent Oxygenase Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.

Full Name

2-Oxoglutarate And Iron Dependent Oxygenase Domain Containing 1

Function

Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation.

Biological Process

Cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-proline hydroxylationManual Assertion Based On ExperimentIDA:CACAO
Protein hydroxylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of translational terminationManual Assertion Based On ExperimentIMP:UniProtKB
Stress granule assemblyManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Isoform 1
Cytoplasm
Nucleus
Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.
Isoform 2
Cytoplasm

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Anti-OGFOD1 antibodies

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Mouse Anti-OGFOD1 Recombinant Antibody (1G6) (CBMAB-O0326-CQ)

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Target: OGFOD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1G6

Application*: F, WB

Mouse Anti-OGFOD1 Recombinant Antibody (1F4) (CBMAB-O0325-CQ)

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Target: OGFOD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1F4

Application*: F, P, WB

Mouse Anti-OGFOD1 Recombinant Antibody (1D9) (CBMAB-1636-CN)

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Target: OGFOD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: 1D9

Application*: WB, F, IF, IH, P

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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