OGFOD1

OGFOD1 (2-Oxoglutarate And Iron Dependent Oxygenase Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.

Full Name

2-Oxoglutarate And Iron Dependent Oxygenase Domain Containing 1

Function

Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation.

Biological Process

Cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-proline hydroxylationManual Assertion Based On ExperimentIDA:CACAO
Protein hydroxylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of translational terminationManual Assertion Based On ExperimentIMP:UniProtKB
Stress granule assemblyManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Isoform 1
Cytoplasm
Nucleus
Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.
Isoform 2
Cytoplasm

Anti-OGFOD1 antibodies

Mouse Anti-OGFOD1 Recombinant Antibody (1D9) (CBMAB-1636-CN)

Datasheet

SDS

Target: OGFOD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: 1D9

Application*: WB, F, IF, IH, P

Mouse Anti-OGFOD1 Recombinant Antibody (1G6) (CBMAB-O0326-CQ)

Datasheet

SDS

Target: OGFOD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1G6

Application*: F, WB

Mouse Anti-OGFOD1 Recombinant Antibody (1F4) (CBMAB-O0325-CQ)

Datasheet

SDS

Target: OGFOD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1F4

Application*: F, P, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)