REG1A
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]
Full Name
Regenerating Family Member 1 Alpha
Function
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell wall disruption in another organismManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell wall disruption in another organismManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
PTM
The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.
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Anti-REG1A antibodies
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CompareTarget: REG1A
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: MM088937T9
Application*: WB, P
Target: REG1A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-380
Application*: E
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-379
Application*: E, P, IF
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6F8H10D4
Application*: E, IF, IF
Target: REG1A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 431211
Application*: WB, IH
Target: REG1A
Host: Mouse
Specificity: Human
Clone: 13j72
Application*: E, ICC, IH, WB
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B674
Application*: E, IH
Target: REG1A
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12K128
Application*: F
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 09
Application*: E
Target: REG1A
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: 431202
Application*: WB, F, MC
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A4
Application*: E, IF, IH
Target: REG1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT1096
Application*: P, IF, IC, E
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3558
Application*: IH, IC
Target: REG1A
Specificity: Human
Target: REG1A
Specificity: Human
Target: REG1A
Specificity: Human
Target: REG1A
Specificity: Human
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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