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REG1A

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]
Full Name
Regenerating Family Member 1 Alpha
Function
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell wall disruption in another organismManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
PTM
The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.

Anti-REG1A antibodies

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Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A4
Application*: E, IF, IH
Target: REG1A
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: MM088937T9
Application*: WB, P
Target: REG1A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-380
Application*: E
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-379
Application*: E, P, IF
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6F8H10D4
Application*: E, IF, IF
Target: REG1A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 431211
Application*: WB, IH
Target: REG1A
Host: Mouse
Specificity: Human
Clone: 13j72
Application*: E, ICC, IH, WB
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B674
Application*: E, IH
Target: REG1A
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12K128
Application*: F
Target: REG1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 09
Application*: E
Target: REG1A
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: 431202
Application*: WB, F, MC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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