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Mouse Anti-REG1A Recombinant Antibody (1A4) (CBMAB-L0059-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Regenerating Family Member 1 Alpha (REG1A). The antibody can be used for immunoassay techniques, such as ELISA, IF, IHC.
See all REG1A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A4
Antibody Isotype
IgG1
Application
ELISA, IF, IHC

Basic Information

Immunogen
Recombinant corresponding to human REG1A.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Preservative
0.03% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Regenerating Family Member 1 Alpha
Introduction
Gene of REG1A is a type I subclass member of the Reg gene family. As a multigene family, the Reg gene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. REG1A is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be take part in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
Entrez Gene ID
5967
UniProt ID
P05451
Alternative Names
Regenerating Family Member 1 Alpha; Pancreatic Thread Protein; Regenerating Islet-Derived Protein 1-Alpha; Islet Of Langerhans Regenerating Protein; Islet Cells Regeneration Factor; Regenerating Protein I Alpha; Pancreatic Stone Protein; REG-1-Alpha; PSPS1; ICRF
Function
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell wall disruption in another organismManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
PTM
The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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