SCYL3

This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms.
Full Name
SCY1 Like Pseudokinase 3
Function
May play a role in regulating cell adhesion/migration complexes in migrating cells.
Biological Process
Biological Process cell migration1 PublicationNAS:UniProtKB
Biological Process inflammatory responseIEA:Ensembl
Biological Process neuron developmentIEA:Ensembl
Biological Process protein localizationIEA:Ensembl
Biological Process protein phosphorylationIEA:InterPro
Biological Process spinal cord motor neuron differentiationIEA:Ensembl
Cellular Location
Cytoplasm
Golgi apparatus
Cell projection, lamellipodium
Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.
PTM
May be myristoylated; myristoylation may target it to Golgi compartment.
Phosphorylated.
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Anti-SCYL3 antibodies

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SCYL3 Matched Antibody Pair (1045) (APMAB-1045LY)

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Target: SCYL3
Specificity: Human
Datasheet SDS

Mouse Anti-SCYL3 Recombinant Antibody (CBXS-3050) (CBMAB-S5796-CQ)

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Target: SCYL3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3050
Application*: E, WB
Datasheet SDS

Mouse Anti-SCYL3 Recombinant Antibody (CBXS-5054) (CBMAB-S2275-CQ)

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Target: SCYL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBXS-5054
Application*: F, IF, IH, P, WB
Datasheet SDS

Mouse Anti-SCYL3 Recombinant Antibody (CBXS-4640) (CBMAB-S1879-CQ)

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Target: SCYL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4640
Application*: F, IH, P, WB
Datasheet SDS

Mouse Anti-SCYL3 Recombinant Antibody (CBXS-3820) (CBMAB-S1091-CQ)

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Target: SCYL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3820
Application*: WB, IH, P
Datasheet SDS

Mouse Anti-SCYL3 Recombinant Antibody (CBXS-5846) (CBMAB-S0701-CQ)

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Target: SCYL3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5846
Application*: WB
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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