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Mouse Anti-SCYL3 Recombinant Antibody (CBXS-5846) (CBMAB-S0701-CQ)

This product is a mouse antibody that recognizes SCYL3. The antibody CBXS-5846 can be used for immunoassay techniques such as: WB.
See all SCYL3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5846
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
Protein expressed in 293T cell transfected with human SCYL3 expression vector
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SCY1 Like Pseudokinase 3
Introduction
This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms.
Entrez Gene ID
57147
UniProt ID
Q8IZE3
Alternative Names
PACE-1; PACE1
Function
May play a role in regulating cell adhesion/migration complexes in migrating cells.
Biological Process
Biological Process cell migration1 PublicationNAS:UniProtKB
Biological Process inflammatory responseIEA:Ensembl
Biological Process neuron developmentIEA:Ensembl
Biological Process protein localizationIEA:Ensembl
Biological Process protein phosphorylationIEA:InterPro
Biological Process spinal cord motor neuron differentiationIEA:Ensembl
Cellular Location
Cytoplasm
Golgi apparatus
Cell projection, lamellipodium
Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.
PTM
May be myristoylated; myristoylation may target it to Golgi compartment.
Phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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