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Mouse Anti-ATP5F1C Recombinant Antibody (2H6) (CBMAB-A4059-YC)

Provided herein is a Mouse monoclonal antibody against Human ATP Synthase F1 Subunit Gamma. The antibody can be used for immunoassay techniques, such as IHC-P, WB.
See all ATP5F1C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2H6
Antibody Isotype
IgG1
Application
IHC, WB

Basic Information

Immunogen
Full length human recombinant protein of human ATP5C1 produced in E.coli.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000
IHC1:150

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ATP Synthase F1 Subunit Gamma
Introduction
ATP5F1C is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked mul
Entrez Gene ID
509
UniProt ID
P36542
Alternative Names
ATP Synthase F1 Subunit Gamma; ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Gamma Polypeptide 1; ATP5C1; F-ATPase Gamma Subunit; ATP5CL1; ATP5C; Mitochondrial ATP Synthase, Gamma Subunit 1; ATP Synthase Subunit Gamma, Mitochondrial; ATP Syntha
Function
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F1 domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha3beta3. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Biological Process
ATP biosynthetic process Source: Reactome
ATP synthesis coupled proton transport Source: GO_Central
Cristae formation Source: Reactome
Mitochondrial ATP synthesis coupled proton transport Source: UniProtKB
Oxidative phosphorylation Source: UniProtKB
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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