Mouse Anti-ATXN1 Recombinant Antibody (CBT4108) (V2LY-0625-LY1130)

Shuvaev, A. N., Belozor, O. S., Mozhei, O., Yakovleva, D. A., Potapenko, I. V., Shuvaev, A. N., ... & Kasparov, S. (2021). Chronic optogenetic stimulation of Bergman glia leads to dysfunction of EAAT1 and Purkinje cell death, mimicking the events caused by expression of pathogenic ataxin-1. Neurobiology of Disease, 154, 105340.

Didonna, A., Puig, E. C., Ma, Q., Matsunaga, A., Ho, B., Caillier, S. J., ... & Oksenberg, J. R. (2020). Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis. Proceedings of the National Academy of Sciences, 117(38), 23742-23750.

O’Callaghan, B., Hofstra, B., Handler, H. P., Kordasiewicz, H. B., Cole, T., Duvick, L., ... & Orr, H. T. (2020). Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment. Molecular Therapy-Nucleic Acids, 21, 1006-1016.

Manek, R., Nelson, T., Tseng, E., & Rodriguez-Lebron, E. (2020). 5′ UTR-mediated regulation of Ataxin-1 expression. Neurobiology of disease, 134, 104564.

Suh, J., Romano, D. M., Nitschke, L., Herrick, S. P., DiMarzio, B. A., Dzhala, V., ... & Tanzi, R. E. (2019). Loss of ataxin-1 potentiates Alzheimer’s pathogenesis by elevating cerebral BACE1 transcription. Cell, 178(5), 1159-1175.

Friedrich, J., Kordasiewicz, H. B., O’Callaghan, B., Handler, H. P., Wagener, C., Duvick, L., ... & Orr, H. T. (2018). Antisense oligonucleotide–mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles. JCI insight, 3(21).

Kang, A. R., An, H. T., Ko, J., Choi, E. J., & Kang, S. (2017). Ataxin-1 is involved in tumorigenesis of cervical cancer cells via the EGFR–RAS–MAPK signaling pathway. Oncotarget, 8(55), 94606.

Kang, A. R., An, H. T., Ko, J., & Kang, S. (2017). Ataxin-1 regulates epithelial–mesenchymal transition of cervical cancer cells. Oncotarget, 8(11), 18248.

Fanslow, D., Cogswell, A., Strojny, C., Garza‐Gongora, A., Smith, E., & Kosak, S. (2017). Repeat expanded Ataxin‐1 mRNA and protein is co‐regulated at PML bodies. The FASEB Journal, 31, 915-7.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols