Mouse Anti-CNKSR1 Recombinant Antibody (EG746) (V2LY-1206-LY423)

Name: Mouse Anti-CNKSR1 Recombinant Antibody (EG746)
SKU: V2LY-1206-LY423
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human

Clone

EG746

Antibody Isotype

IgG1

Application

Basic Information

Immunogen

CNKSR1 Fusion Protein (308-720 aa).

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:1,000-1:4,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Connector Enhancer Of Kinase Suppressor Of Ras 1

Entrez Gene ID

10256

UniProt ID

Q969H4

Function

May function as an adapter protein or regulator of Ras signaling pathways.

Biological Process

Ras protein signal transduction Source: MGI
Rho protein signal transduction Source: MGI
Transmembrane receptor protein tyrosine kinase signaling pathway Source: ProtInc

Cellular Location

Cytoplasm; Membrane

PTM

Phosphorylated on tyrosine.

More Infomation

References

Nishiyama, K., Maekawa, M., Nakagita, T., Nakayama, J., Kiyoi, T., Chosei, M., ... & Higashiyama, S. (2021). CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP. Life Science Alliance, 4(9).

Kazeminasab, S., Taskiran, I. I., Fattahi, Z., Bazazzadegan, N., Hosseini, M., Rahimi, M., ... & Kahrizi, K. (2018). CNKSR1 gene defect can cause syndromic autosomal recessive intellectual disability. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 177(8), 691-699.

Quadri, H. S., Aiken, T. J., Allgaeuer, M., Moravec, R., Altekruse, S., Hussain, S. P., ... & Rudloff, U. (2017). Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer. BMC cancer, 17(1), 1-12.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CNKSR1 Recombinant Antibody (CBWJC-2852)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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