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Mouse Anti-CRKL Recombinant Antibody (CBFYC-2215) (V2LY-1206-LY1185)

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Published Data

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBFYC-2215
Antibody Isotype
IgG2b, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 181-242 of human Crk-L.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1% gelatin
Preservative
0.09% sodium azide
Concentration
0.2 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CRK Like Proto-Oncogene, Adaptor Protein
Entrez Gene ID
Human1399
Mouse12929
Rat287942
UniProt ID
HumanP46109
MouseP47941
RatQ5U2U2
Function
May mediate the transduction of intracellular signals.
Biological Process
Acetylcholine receptor signaling pathway Source: Ensembl
Activation of GTPase activity Source: Ensembl
Activation of MAPK activity Source: Ensembl
Activation of MAPKK activity Source: Reactome
Anterior/posterior pattern specification Source: Ensembl
B cell apoptotic process Source: Ensembl
Blood vessel development Source: Ensembl
Cell chemotaxis Source: Ensembl
Cellular response to drug Source: Ensembl
Cellular response to interleukin-7 Source: Ensembl
Cellular response to transforming growth factor beta stimulus Source: ARUK-UCL
Cerebellar neuron development Source: Ensembl
Cerebral cortex development Source: Ensembl
Cranial skeletal system development Source: Ensembl
Cytokine-mediated signaling pathway Source: Reactome
Dendrite development Source: Ensembl
Endothelin receptor signaling pathway Source: Ensembl
Establishment of cell polarity Source: Ensembl
Fibroblast growth factor receptor signaling pathway Source: Ensembl
Helper T cell diapedesis Source: Ensembl
Hippocampus development Source: Ensembl
Intracellular signal transduction Source: ProtInc
JNK cascade Source: ProtInc
Lipid metabolic process Source: Ensembl
Male gonad development Source: Ensembl
Negative regulation of gene expression Source: ARUK-UCL
Negative regulation of protein phosphorylation Source: ARUK-UCL
Neuron migration Source: Ensembl
Outflow tract morphogenesis Source: Ensembl
Parathyroid gland development Source: Ensembl
Pharynx development Source: Ensembl
Positive regulation of cell population proliferation Source: CACAO
Positive regulation of ERK1 and ERK2 cascade Source: ARUK-UCL
Positive regulation of glial cell migration Source: ARUK-UCL
Positive regulation of protein phosphorylation Source: ARUK-UCL
Positive regulation of Ras protein signal transduction Source: Reactome
Positive regulation of substrate adhesion-dependent cell spreading Source: UniProtKB
Ras protein signal transduction Source: ProtInc
Reelin-mediated signaling pathway Source: Ensembl
Regulation of cell adhesion mediated by integrin Source: Ensembl
Regulation of cell growth Source: Ensembl
Regulation of dendrite development Source: Ensembl
Regulation of skeletal muscle acetylcholine-gated channel clustering Source: Ensembl
Regulation of T cell migration Source: Ensembl
Retinoic acid receptor signaling pathway Source: Ensembl
Single fertilization Source: Ensembl
Spermatogenesis Source: Ensembl
Synapse assembly Source: Ensembl
T cell receptor signaling pathway Source: Ensembl
Thymus development Source: Ensembl
Urogenital system development Source: Ensembl
Cellular Location
Cytosol; Nucleoplasm; Extrinsic component of postsynaptic membrane; Neuromuscular junction; Protein-containing complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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