Mouse Anti-DEFA3 Recombinant Antibody (1A9) (V2LY-0425-LY154)

Name: Mouse Anti-DEFA3 Recombinant Antibody (1A9)
SKU: V2LY-0425-LY154
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1A9

Application

WB, ELISA

Immunogen

DEFA3 full-length recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

defensin, alpha 3, neutrophil-specific

Entrez Gene ID

1668

UniProt ID

P59666

Function

Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Biological Process

Antibacterial humoral response Source: UniProtKB
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Antimicrobial humoral response Source: Reactome
Cellular response to lipopolysaccharide Source: GO_Central
Defense response to fungus Source: UniProtKB-KW
Defense response to Gram-negative bacterium Source: GO_Central
Defense response to Gram-positive bacterium Source: UniProtKB
Defense response to virus Source: UniProtKB-KW
Innate immune response in mucosa Source: UniProtKB
Intracellular estrogen receptor signaling pathway Source: UniProtKB
Killing of cells of other organism Source: UniProtKB
Membrane disruption in other organism Source: GO_Central

Cellular Location

Secreted

Chen, Q., Yang, Y., Hou, J., Shu, Q., Yin, Y., Fu, W., ... & Fang, X. (2019). Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis. Proceedings of the National Academy of Sciences, 116(8), 3161-3170.

Maneerat, Y., Prasongsukarn, K., Benjathummarak, S., & Dechkhajorn, W. (2017). PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease. Lipids in health and disease, 16(1), 1-12.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

Mouse Anti-DEFA3 Recombinant Antibody (1A9) (CAT#: CBMAB-A2181-LY)

Related Products

Mouse Anti-DEFA3 Recombinant Antibody (1A9) (CAT#: CBMAB-A2181-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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