Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-FNDC3A Recombinant Antibody (CBXF-0800) (CBMAB-F0449-CQ)


See all FNDC3A antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0800
Antibody Isotype
IgG2b, κ
Application
ELISA, IF, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
fibronectin type III domain containing 3A
Introduction
FNDC3A (Fibronectin Type III Domain Containing 3A) is a Protein Coding gene. Diseases associated with FNDC3A include Holoprosencephaly 3. An important paralog of this gene is FNDC3B.
Entrez Gene ID
22862
UniProt ID
Q9Y2H6
Alternative Names
Fibronectin Type III Domain Containing 3A; Human Gene Expressed In Odontoblasts; FNDC3; HUGO; Fibronectin Type-III Domain-Containing Protein 3A; Fibronectin Type III Domain Containing 3; BA203I16.1; BA203I16.5; KIAA0970;
Function
Mediates spermatid-Sertoli adhesion during spermatogenesis.
Biological Process
Cell-cell adhesion Source: Ensembl
Fertilization Source: Ensembl
Sertoli cell development Source: Ensembl
Spermatid development Source: Ensembl
Cellular Location
Golgi apparatus membrane
Topology
Helical: 1177-1197
More Infomation

Liedtke, D., & Klopocki, E. (2022). Microarray expression profiling of fndc3a zebrafish mutants. Micropublication Biology, 2022.

Manfrini, N., Mancino, M., Miluzio, A., Oliveto, S., Balestra, M., Calamita, P., ... & Biffo, S. (2020). FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and AutophagyRole of the FAM46C/FNDC3A Complex in Multiple Myeloma. Cancer Research, 80(21), 4693-4706.

Fucci, C., Resnati, M., Riva, E., Perini, T., Ruggieri, E., Orfanelli, U., ... & Milan, E. (2020). The interaction of the tumor suppressor FAM46C with p62 and FNDC3 proteins integrates protein and secretory homeostasis. Cell Reports, 32(12), 108162.

Liedtke, D., Orth, M., Meissler, M., Geuer, S., Knaup, S., Köblitz, I., & Klopocki, E. (2019). ECM alterations in Fndc3a (fibronectin domain containing protein 3A) deficient zebrafish cause temporal fin development and regeneration defects. Scientific Reports, 9(1), 13383.

Syed, A., Lukacsovich, T., Pomeroy, M., Bardwell, A. J., Decker, G. T., Waymire, K. G., ... & MacGregor, G. R. (2019). Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila. Developmental biology, 445(1), 37-53.

Liedtke, D., Orth, M., Meissler, M., Geuer, S., Knaup, S., Köblitz, I., & Klopocki, E. (2018). Fndc3a (Fibronectin Domain Containing Protein 3A) influences median fin fold development and caudal fin regeneration in zebrafish by ECM alteration. bioRxiv, 386813.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-FNDC3A Recombinant Antibody (CBXF-0800)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry