Mouse Anti-GALT Recombinant Antibody (CBLNG-183) (CBMAB-1558-CN)

Name: Mouse Anti-GALT Recombinant Antibody (CBLNG-183)
SKU: CBMAB-1558-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBLNG-183

Application

ELISA, WB, IHC-P

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Concentration

0.25 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Galactose-1-Phosphate Uridylyltransferase

Introduction

GALT catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of GALT results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet.

Entrez Gene ID

2592

UniProt ID

P07902

Alternative Names

galactose-1-phosphate uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; gal-1-P uridylyltransferase; galactose-1-phosphate uridyl transferase; EC 2.7.7.12

Function

Plays an important role in galactose metabolism.

Biological Process

Galactose catabolic process Source: Reactome
Galactose catabolic process via UDP-galactose Source: GO_Central
Galactose metabolic process Source: UniProtKB
UDP-glucose catabolic process Source: Ensembl
UDP-glucose metabolic process Source: UniProtKB

Cellular Location

Cytosol; Golgi apparatus; Cytoplasm

Involvement in disease

Galactosemia 1 (GALAC1):
A form of galactosemia, an inborn error of galactose metabolism typically manifesting in the neonatal period, after ingestion of galactose, with jaundice, hepatosplenomegaly, hepatocellular insufficiency, food intolerance, hypoglycemia, renal tubular dysfunction, muscle hypotonia, sepsis and cataract. GALAC1 inheritance is autosomal recessive.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

GALT Matched Antibody Pair (462) (CAT#: APMAB-462LY)

GALT Matched Antibody Pair (463) (CAT#: APMAB-463LY)

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GALT Matched Antibody Pair (462) (CAT#: APMAB-462LY)

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GALT Matched Antibody Pair (463) (CAT#: APMAB-463LY)

Rabbit Anti-GALT Recombinant Antibody (CBLG1-2565) (CAT#: CBMAB-G1875-LY)

Mouse Anti-GALT Recombinant Antibody (CBLG1-514) (CAT#: CBMAB-G1878-LY)

Mouse Anti-GALT Monoclonal Antibody (4C11) (CAT#: CBMAB-1319-YC)

Mouse Anti-GALT Recombinant Antibody (CBFYH-0235) (CAT#: CBMAB-H1105-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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