Rabbit Anti-PRKCSH Recombinant Antibody (EG1334) (CBMAB-EN1612-LY)

Name: Rabbit Anti-PRKCSH Recombinant Antibody (EG1334)
SKU: CBMAB-EN1612-LY
Rating: 5 (1 reviews)

See all PRKCSH antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1334

Application

WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human GLU2B.

Specificity

Human, Mouse

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

protein kinase C substrate 80K-H

Introduction

This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

Human	5589
Mouse	19089

UniProt ID

Human	P14314
Mouse	O08795

Alternative Names

GIIB; PCLD; PLD1; G19P1; PCLD1; PKCSH; AGE-R2; VASAP-60

Function

Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature glycoproteins (PubMed:10929008).
Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity).

Biological Process

Intracellular signal transduction2 PublicationsNAS:UniProtKB
Liver developmentManual Assertion Based On ExperimentIBA:GO_Central
N-glycan processingManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Endoplasmic reticulum

Involvement in disease

Polycystic liver disease 1 with or without kidney cysts (PCLD1):
An autosomal dominant hepatobiliary disease characterized by overgrowth of biliary epithelium and supportive connective tissue, resulting in multiple liver cysts. A subset of patients may develop kidney cysts that usually do not result in clinically significant renal disease.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-PRKCSH Recombinant Antibody (EG1334)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

PRKCSH Matched Antibody Pair (928) (CAT#: APMAB-928LY)

Related Products

PRKCSH Matched Antibody Pair (928) (CAT#: APMAB-928LY)

Mouse Anti-PRKCSH Recombinant Antibody (3H7) (CAT#: CBMAB-P2857-YC)

Rabbit Anti-PRKCSH Recombinant Antibody (CBLG1-3097) (CAT#: CBMAB-G6476-LY)

Mouse Anti-PRKCSH Recombinant Antibody (CBLG1-3241) (CAT#: CBMAB-G6474-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry