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Mouse Anti-GMNN Recombinant Antibody (1A8) (CBMAB-G4021-LY)

This product is antibody recognizes GMNN. The antibody 1A8 immunoassay techniques such as: ELISA (EL/EIA), WB.
Host Animal
Mouse
Application
ELISA (EL/EIA), WB
Immunogen
Recognizes human GMNN
Antibody Isotype
IgG1, κ
Specificity
Human
Cross Reactivity
Human
Clone
1A8
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
Alternative Name
Geminin; DNA Replication Inhibitor; Geminin; MGORS6; Gem;
Entrez Gene ID
UniProt ID
Cat CBMAB-G4021-LY
Conjugates
Size
Price $
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