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Mouse Anti-GNA14 Recombinant Antibody (CBLG1-1386) (CBMAB-G4066-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-1386
Antibody Isotype
IgG1, κ
Application
S-ELISA, IHC-P, WB

Basic Information

Immunogen
GNA14 (AAH27886.1, 150 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G protein subunit alpha 14
Introduction
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]
Entrez Gene ID
9630
UniProt ID
O95837
Alternative Names
G Protein Subunit Alpha 14; Guanine Nucleotide Binding Protein (G Protein); Alpha 14; G-Protein Subunit Alpha-14; G Alpha-14;
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Biological Process
Action potential Source: GO_Central
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Phospholipase C-activating dopamine receptor signaling pathway Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Extracellular exosome; Heterotrimeric G-protein complex; Plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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