Mouse Anti-GORAB Recombinant Antibody (CBLG1-2878) (CBMAB-G4371-LY)

Name: Mouse Anti-GORAB Recombinant Antibody (CBLG1-2878)
SKU: CBMAB-G4371-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBLG1-2878

Application

Immunogen

Human recombinant protein fragment corresponding to amino acids 35-394 of human GORAB(NP_689494) produced in E.coli

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

50% glycerol

Preservative

0.02% NaN3

Concentration

1 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Golgin, RAB6 Interacting

Introduction

This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

Entrez Gene ID

92344

UniProt ID

Q5T7V8

Alternative Names

Golgin; RAB6 Interacting; N-Terminal Kinase-Like-Binding Protein 1; SCY1-Like 1-Binding Protein 1; RAB6-Interacting Golgin; SCYL1-Binding Protein 1; NTKL-Binding Protein 1; SCYL1-BP1; HNTKL-BP1;

Biological Process

Hair follicle morphogenesis Source: Ensembl
Non-motile cilium assembly Source: GO_Central
Positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl

Cellular Location

Cytoplasm; Golgi apparatus

Involvement in disease

Geroderma osteodysplasticum (GO):
A rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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