Rabbit Anti-GPR32 Recombinant Antibody (EG1400) (CBMAB-EN1679-LY)

Name: Rabbit Anti-GPR32 Recombinant Antibody (EG1400)
SKU: CBMAB-EN1679-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1400

Application

WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human GPR32.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

G Protein-Coupled Receptor 32

Introduction

This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19. [provided by RefSeq, Nov 2012]

Entrez Gene ID

2854

UniProt ID

O75388

Alternative Names

G Protein-Coupled Receptor 32; Resolvin D1 Receptor; Probable G-Protein Coupled Receptor 32; RVDR1;

Function

Orphan receptor.

Biological Process

Complement receptor mediated signaling pathway Source: GO_Central
G protein-coupled receptor signaling pathway Source: ProtInc
Inflammatory response Source: GO_Central
Phospholipase C-activating G protein-coupled receptor signaling pathway Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-44
Helical: 45-67
Cytoplasmic: 68-78
Helical: 79-100
Extracellular: 101-116
Helical: 117-137
Cytoplasmic: 138-156
Helical: 157-178
Extracellular: 179-220
Helical: 221-241
Cytoplasmic: 242-257
Helical: 258-280
Extracellular: 281-300
Helical: 301-320
Cytoplasmic: 321-356

Merlin, J., Park, J., Vandekolk, T. H., Fabb, S. A., Allinne, J., Summers, R. J., ... & Riddy, D. M. (2022). Multipathway In vitro pharmacological characterization of specialized proresolving G protein-coupled receptors. Molecular Pharmacology, 101(4), 246-256.

Alexander, S. P., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A., Peters, J. A., ... & Ward, D. T. (2021). The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors. British journal of pharmacology, 178, S27-S156.

Mastromarino, M., Lacivita, E., Colabufo, N. A., & Leopoldo, M. (2020). G-protein coupled receptors involved in the resolution of inflammation: Ligands and therapeutic perspectives. Mini Reviews in Medicinal Chemistry, 20(20), 2090-2103.

Rinne, M., Tanoli, Z. U. R., Khan, A., & Xhaard, H. (2019). Cartography of rhodopsin-like G protein-coupled receptors across vertebrate genomes. Scientific Reports, 9(1), 1-16.

Laschet, C., Dupuis, N., & Hanson, J. (2018). The G protein-coupled receptors deorphanization landscape. Biochemical Pharmacology, 153, 62-74.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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