Detects endogenous levels of GSK-3 alpha only when phosphorylated at Ser21. Species Crossreactivity: Human, mouse, rat, monkey and zebra fish
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]
Glycogen Synthase Kinase 3 Alpha; EC 18.104.22.168; Serine/Threonine-Protein Kinase GSK3A; GSK-3 Alpha; EC 22.214.171.124; EC 2.7.11;