Mouse Anti-GTPBP1 Recombinant Antibody (CBFYH-0538) (CBMAB-H0610-FY)

Name: Mouse Anti-GTPBP1 Recombinant Antibody (CBFYH-0538)
SKU: CBMAB-H0610-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0538

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

GTP binding protein 1

Introduction

The primary structure of GTPBP1 is highly conserved between human and mouse.

Entrez Gene ID

9567

UniProt ID

O00178

Alternative Names

GTP Binding Protein 1; G-Protein 1; GP-1; GP1; GTP-Binding Protein 1; HSPC018

Function

Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity).

Biological Process

GTP metabolic process Source: UniProtKB
Immune response Source: ProtInc
Positive regulation of mRNA catabolic process Source: UniProtKB
Signal transduction Source: ProtInc
Translational elongation Source: GO_Central

Cellular Location

Cytoplasm

Terrey, M., Adamson, S. I., Gibson, A. L., Deng, T., Ishimura, R., Chuang, J. H., & Ackerman, S. L. (2021). Correction: GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis. Elife, 10, e70785.

Terrey, M., Adamson, S. I., Gibson, A. L., Deng, T., Ishimura, R., Chuang, J. H., & Ackerman, S. L. (2020). GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis. Elife, 9, e62731.

Zinoviev, A., Goyal, A., Jindal, S., LaCava, J., Komar, A. A., Rodnina, M. V., ... & Pestova, T. V. (2018). Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2. Genes & Development, 32(17-18), 1226-1241.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-GTPBP1 Recombinant Antibody (CBLG1-2138) (CAT#: CBMAB-G5752-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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