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Mouse Anti-MAP3K7 Recombinant Antibody (2E10) (CBMAB-A5219-LY)

The product is antibody recognizes MAP3K7. The antibody 2E10 immunoassay techniques such as: WB, ELISA.
Host Species
Mouse
Application
WB, ELISA
Immunogen
MAP3K7 (AAH17715, 1 a.a. ~ 579 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
2E10
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Alternative Name
TAK1; TGF1a
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-A5219-LY
Conjugates
Size
Price $
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Second antibody and isotype control