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Mouse Anti-MAPK10 Recombinant Antibody (4E12-1F7) (CBMAB-A5235-LY)

The product is antibody recognizes MAPK10. The antibody 4E12-1F7 immunoassay techniques such as: WB, ELISA.
Host Species
Mouse
Application
WB, ELISA
Immunogen
MAPK10 (AAH65516, 219 a.a. ~ 319 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
4E12-1F7
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Alternative Name
FLJ12099; FLJ33785; JNK3; JNK3A; MGC50974; PRKM10; p493F12; p54bSAPK
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-A5235-LY
Conjugates
Size
Price $
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Second antibody and isotype control