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Rabbit Anti-Phospho-CHEK1 (Ser296) Recombinant Antibody (D3O9F) (CBMAB-CP0301-LY)

The product is antibody recognizes Phospho-CHEK1 (Ser296). The antibody D3O9F immunoassay techniques such as: WB.
Host Animal
Rabbit
Application
WB
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser296 of human Chk1 protein.
Antibody Isotype
IgG
Cross Reactivity
Human, Mouse, Rat
Clone
D3O9F
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
Alternative Name
Checkpoint Kinase 1; Cell Cycle Checkpoint Kinase; CHK1 Checkpoint Homolog; EC 2.7.11.1; CHK1; Serine/Threonine-Protein Kinase Chk1; Checkpoint; S. Pombe; Homolog Of; 1;
Entrez Gene ID
UniProt ID
Cat CBMAB-CP0301-LY
Conjugates
Size
Price $
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