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Mouse Anti-SLC16A11 Recombinant Antibody (CBFYM-3126) (CBMAB-M3323-FY)

This product is mouse antibody that recognizes SLC16A11. The antibody CBFYM-3126 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all SLC16A11 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-3126
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SOLUTE CARRIER FAMILY 16 MEMBER 11
Introduction
Genetic variants in SLC16A11 were recently reported to be associated with type 2 diabetes in Mexican and other Latin American populations.
Entrez Gene ID
162515
UniProt ID
Q8NCK7
Alternative Names
Solute Carrier Family 16 Member 11; Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 11; Monocarboxylic Acid Transporter 11; MCT 11; MCT11; Solute Carrier Family 16, Member 11; Monocarboxylate Transporter 11
Function
Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane (PubMed:28666119).
Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids (PubMed:24390345).
Biological Process
Biological Process lipid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process monocarboxylic acid transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum membrane
Cell membrane
Involvement in disease
Diabetes mellitus, non-insulin-dependent (NIDDM):
A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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