Mouse Anti-THRB Recombinant Antibody (J52) (CBMAB-T2294-YJ)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process cellular response to thyroid hormone stimulusSource:ARUK-UCL1 Publication
Biological Process DNA-templated transcriptionSource:ProtInc1 Publication
Biological Process female courtship behaviorSource:Ensembl
Biological Process hormone-mediated signaling pathwaySource:GO_Central1 Publication
Biological Process mRNA transcription by RNA polymerase IISource:ComplexPortal1 Publication
Biological Process negative regulation of female receptivitySource:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Biological Process positive regulation of thyroid hormone mediated signaling pathwaySource:ComplexPortal1 Publication
Biological Process positive regulation of transcription by RNA polymerase IISource:ComplexPortal1 Publication
Biological Process regulation of heart contractionSource:Ensembl
Biological Process retinal cone cell apoptotic processSource:Ensembl
Biological Process retinal cone cell developmentSource:Ensembl
Biological Process sensory perception of soundSource:Ensembl
Biological Process thyroid hormone mediated signaling pathwaySource:GO_Central1 Publication
Biological Process type I pneumocyte differentiationSource:Ensembl
An autosomal dominant disease characterized by high levels of circulating thyroid hormones (T3-T4), goiter, abnormal mental functions, increased susceptibility to infections, abnormal growth and bone maturation, tachycardia and deafness. Affected individuals may also have attention deficit-hyperactivity disorders (ADHD) and language difficulties. Patients have normal or slightly elevated thyroid stimulating hormone (TSH).
Thyroid hormone resistance, generalized, autosomal recessive (GRTHR):
An autosomal recessive disorder characterized by goiter, clinical euthyroidism, end-organ unresponsiveness to thyroid hormone, abnormal growth and bone maturation, and deafness. Patients also have high levels of circulating thyroid hormones, with elevated thyroid stimulating hormone.
Selective pituitary thyroid hormone resistance (PRTH):
Variant form of thyroid hormone resistance and is characterized by clinical hyperthyroidism, with elevated free thyroid hormones, but inappropriately normal serum TSH. Unlike GRTH, where the syndrome usually segregates with a dominant allele, the mode of inheritance in PRTH has not been established.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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