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APOM

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
Full Name
Apolipoprotein M
Function
Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
Biological Process
Cholesterol efflux Source: BHF-UCL
Cholesterol homeostasis Source: BHF-UCL
High-density lipoprotein particle assembly Source: BHF-UCL
High-density lipoprotein particle clearance Source: BHF-UCL
High-density lipoprotein particle remodeling Source: BHF-UCL
Lipoprotein metabolic process Source: Ensembl
Negative regulation of plasma lipoprotein oxidation Source: BHF-UCL
Response to glucose Source: Ensembl
Retinoid metabolic process Source: Reactome
Reverse cholesterol transport Source: BHF-UCL
Cellular Location
Secreted. Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins (LDL).

Anti-APOM antibodies

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Target: APOM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CAP162
Application*: WB, IP, IF, E, P
Target: APOM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6H3
Application*: WB, E
Target: APOM
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3C7
Application*: WB, E
Target: APOM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2A8
Application*: E, IF
Target: APOM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1G9
Application*: WB, E
Target: APOM
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: V2-611261
Application*: WB, E
Target: APOM
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: D-4
Application*: WB, IP, IF, E
Target: APOM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4C7
Application*: E, WB
Target: APOM
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2E5
Application*: E, WB
Target: APOM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F10
Application*: E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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