BET1

This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgicomplex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternative splicing results in multiple transcript variants.

Bet1 Golgi Vesicular Membrane Trafficking Protein

Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity).

COPII vesicle coating Source: Reactome
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
Protein transport Source: UniProtKB-KW
Vesicle fusion with Golgi apparatus Source: GO_Central

Cis-Golgi network membrane; Golgi apparatus membrane; Endoplasmic reticulum membrane. Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus (By similarity).

Cytoplasmic: 1-94 aa
Helical: 95-115 aa
Vesicular: 116-118 aa