BPIFA2
This gene encodes a member of the palate, lung and nasal epithelium clone (Plunc) family of proteins. Members of this family have been proposed to play a role in the local antibacterial response in nose, mouth and upper respiratory pathways. The encoded soluble salivary protein binds bacterial lipopolysaccharide (LPS) and inhibits bacterial growth. This gene is present in a gene cluster on chromosome 20. Alternative splicing results in multiple transcript variants.
Full Name
BPI Fold Containing Family A Member 2
Function
Has strong antibacterial activity against P. aeruginosa.
Biological Process
Antimicrobial humoral response Source: Reactome
Defense response to bacterium Source: UniProtKB-KW
Defense response to bacterium Source: UniProtKB-KW
Cellular Location
Secreted
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Anti-BPIFA2 antibodies
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Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F12
Application*: WB, P, E, FC, IC/IF
Target: Bpifa2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2063
Application*: IH, F
Target: Bpifa2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3948
Application*: IH, F
Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4612
Application*: F
Target: Bpifa2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBT2395
Application*: IH, IC, F
Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2704
Application*: F
Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B4F5
Application*: WB, FC, E, IH
Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0888
Application*: E, FC, WB
Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0034
Application*: WB, FC, E, IH
Target: BPIFA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0739
Application*: E, FC, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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