BPIFB1
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20.
Full Name
BPI Fold Containing Family B Member 1
Function
May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS.
Biological Process
Antimicrobial humoral response Source: Reactome
Innate immune response in mucosa Source: UniProtKB
Negative regulation of toll-like receptor 4 signaling pathway Source: UniProtKB
Innate immune response in mucosa Source: UniProtKB
Negative regulation of toll-like receptor 4 signaling pathway Source: UniProtKB
Cellular Location
Secreted
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Anti-BPIFB1 antibodies
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Target: Bpifb1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBT3484
Application*: WB
Target: Bpifb1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBT4160
Application*: IH, IC, F
Target: BPIFB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2562
Application*: IH, IC, F
Target: BPIFB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJL-216
Application*: WB, E
Target: BPIFB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-2110
Application*: E, FC, IC, IF, P, WB
Target: BPIFB1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-1976
Application*: WB
Target: BPIFB1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1907
Application*: E
Target: BPIFB1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-1672
Application*: E
Target: BPIFB1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-0740
Application*: P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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