Mouse Anti-Bpifb1 Recombinant Antibody (CBT3484) (V2LY-0625-LY2799)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBT3484
Application
WB
Immunogen
Purified recombinant fragment of mouse Lplunc1 (AA: 248-475) expressed in E. Coli.
Host Species
Mouse
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
BPI Fold Containing Family B Member 1
Entrez Gene ID
UniProt ID
Function
May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS.
Biological Process
Antimicrobial humoral response Source: Reactome
Innate immune response in mucosa Source: UniProtKB
Negative regulation of toll-like receptor 4 signaling pathway Source: UniProtKB
Cellular Location
Secreted

Jiang, X., Deng, X., Wang, J., Mo, Y., Shi, L., Wei, F., ... & Zeng, Z. (2021). BPIFB1 Inhibits Vasculogenic Mimicry Via Downregulation Of GLUT1-Mediated H3K27 Acetylation In Nasopharyngeal Carcinoma.

Li, J., Xu, P., Wang, L., Feng, M., Chen, D., Yu, X., & Lu, Y. (2020). Molecular biology of BPIFB1 and its advances in disease. Annals of translational medicine, 8(10).

Xu, Y., Tao, Z., Jiang, Y., Liu, T., & Xiang, Y. (2019). Overexpression of BPIFB1 promotes apoptosis and inhibits proliferation via the MEK/ERK signal pathway in nasopharyngeal carcinoma. International journal of clinical and experimental pathology, 12(1), 356.

De Smet, E. G., Seys, L. J., Verhamme, F. M., Vanaudenaerde, B. M., Brusselle, G. G., Bingle, C. D., & Bracke, K. R. (2018). Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD. International journal of chronic obstructive pulmonary disease, 13, 11.

Wei, F., Wu, Y., Tang, L., He, Y., Shi, L., Xiong, F., ... & Zeng, Z. (2018). BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM. British journal of cancer, 118(2), 233-247.

Wei, F., Tang, L., He, Y., Wu, Y., Shi, L., Xiong, F., ... & Zeng, Z. (2018). BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression. Cell death & disease, 9(4), 1-12.

Wei, F., Wu, Y., Tang, L., He, Y., Shi, L., Xiong, F., ... & Xiang, B. (2017). BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma through interaction with VTN and VIM. Br J Cancer.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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