Sign in or Register   Sign in or Register
  |  

Rabbit Anti-BPIFB1 Recombinant Antibody (CBYY-0740) (CBMAB-0743-YY)

This product is rabbit antibody that recognizes BPIFB1. The antibody CBYY-0740 can be used for immunoassay techniques such as: IHC-P
See all BPIFB1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBYY-0740
Antibody Isotype
IgG
Application
IHC-P

Basic Information

Immunogen
Recombinant Human BPIFB1 / LPLUNC1 Protein (Catalog#13275-H08H)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
BPI Fold Containing Family B Member 1
Introduction
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20.
Entrez Gene ID
92747
UniProt ID
Q8TDL5
Alternative Names
BPI Fold Containing Family B Member 1; Von Ebner Minor Salivary Gland Protein; Long Palate, Lung And Nasal Epithelium Carcinoma-Associated Protein 1; C20orf114; LPLUNC1; VEMouseGP; Long Palate, Lung And Nasal Epithelium Carcinoma Associated 1; BPI Fold-Containing Family B Member 1; Chromosome 20 Open Reading Frame 114;
Function
May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS.
Biological Process
Antimicrobial humoral response Source: Reactome
Innate immune response in mucosa Source: UniProtKB
Negative regulation of toll-like receptor 4 signaling pathway Source: UniProtKB
Cellular Location
Secreted

Jiang, X., Deng, X., Wang, J., Mo, Y., Shi, L., Wei, F., ... & Zeng, Z. (2021). BPIFB1 Inhibits Vasculogenic Mimicry Via Downregulation Of GLUT1-Mediated H3K27 Acetylation In Nasopharyngeal Carcinoma.

Li, J., Xu, P., Wang, L., Feng, M., Chen, D., Yu, X., & Lu, Y. (2020). Molecular biology of BPIFB1 and its advances in disease. Annals of translational medicine, 8(10).

Xu, Y., Tao, Z., Jiang, Y., Liu, T., & Xiang, Y. (2019). Overexpression of BPIFB1 promotes apoptosis and inhibits proliferation via the MEK/ERK signal pathway in nasopharyngeal carcinoma. International journal of clinical and experimental pathology, 12(1), 356.

De Smet, E. G., Seys, L. J., Verhamme, F. M., Vanaudenaerde, B. M., Brusselle, G. G., Bingle, C. D., & Bracke, K. R. (2018). Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD. International journal of chronic obstructive pulmonary disease, 13, 11.

Wei, F., Wu, Y., Tang, L., He, Y., Shi, L., Xiong, F., ... & Zeng, Z. (2018). BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM. British journal of cancer, 118(2), 233-247.

Wei, F., Tang, L., He, Y., Wu, Y., Shi, L., Xiong, F., ... & Zeng, Z. (2018). BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression. Cell death & disease, 9(4), 1-12.

Wei, F., Wu, Y., Tang, L., He, Y., Shi, L., Xiong, F., ... & Xiang, B. (2017). BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma through interaction with VTN and VIM. Br J Cancer.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-BPIFB1 Recombinant Antibody (CBYY-0740)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare