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CDH6

CDH6 (Cadherin 6) is a Protein Coding gene. Diseases associated with CDH6 include Renal Cell Carcinoma, Nonpapillary. Among its related pathways are Ectoderm Differentiation and ERK Signaling. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH10.

Full Name

Cadherin 6

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Biological Process

Adherens junction organization Source: GO_Central
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Source: GO_Central
Cell adhesion Source: ProtInc
Cell-cell adhesion via plasma-membrane adhesion molecules Source: GO_Central
Cell-cell junction assembly Source: GO_Central
Cell morphogenesis Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Multicellular organism development Source: GO_Central
Notch signaling pathway Source: Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 54-615
Helical: 616-636
Cytoplasmic: 637-790

Anti-CDH6 antibodies

Mouse Anti-CDH6 Antibody (CCD6B-1) (CBMAB-1055CQ)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1, λ

Specificity: Chicken, Human

Clone: CCD6B-1

Application*: IF, IH, WB

Mouse Anti-CDH6 Recombinant Antibody (CBXC-1187) (CBMAB-C1453-CQ)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-1187

Application*: F

Mouse Anti-CDH6 Recombinant Antibody (CBXC-2055) (CBMAB-C0120-CQ)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: CBXC-2055

Application*: WB, IF, P, C

Mouse Anti-CDH6 Recombinant Antibody (CBFYC-1573) (CBMAB-C1632-FY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-1573

Application*: E

Mouse Anti-CDH6 Recombinant Antibody (A101) (CBMAB-AP4047LY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: A101

Application*: ICC, IHC, WB

Rabbit Anti-CDH6 Recombinant Antibody (D3T3I) (CBMAB-CP0260-LY)

SDS

Target: CDH6

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: D3T3I

Application*: WB, IP, P, F

Mouse Anti-CDH6 Recombinant Antibody (CBYY-C1748) (CBMAB-C3186-YY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: CBYY-C1748

Application*: IC, IH, WB

Mouse Anti-CDH6 Recombinant Antibody (CBYY-C0220) (CBMAB-C0634-YY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C0220

Application*: F

Mouse Anti-CDH6 Recombinant Antibody (CBYY-C0219) (CBMAB-C0633-YY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG3

Specificity: Human

Clone: CBYY-C0219

Application*: IH

Mouse Anti-CDH6 Recombinant Antibody (4A10) (CBMAB-C6539-LY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat

Clone: 4A10

Application*: IC, C, WB

Mouse Anti-CDH6 Recombinant Antibody (2F2) (CBMAB-C5069-LY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2F2

Application*: E, WB

Mouse Anti-CDH6 Recombinant Antibody (427903) (CBMAB-C1285-LY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG3

Specificity: Human

Clone: 427903

Application*: IH

Rabbit Anti-CDH6 Recombinant Antibody (CBLY1-015) (CBMAB-K0262-LY)

SDS

Target: CDH6

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBLY1-015

Application*: WB, IP

Mouse Anti-CDH6 Recombinant Antibody (427909) (CBMAB-K0264-LY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 427909

Application*: F, IC, IF, WB

Mouse Anti-CDH6 Recombinant Antibody (2B6) (CBMAB-K0263-LY)

SDS

Target: CDH6

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat

Clone: 2B6

Application*: IH, C, P, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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