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CSTF3

The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Full Name

cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa

Function

One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.

Biological Process

mRNA 3'-end processing Source: Reactome
mRNA cleavage Source: ProtInc
mRNA polyadenylation Source: ProtInc
mRNA splicing, via spliceosome Source: Reactome
RNA 3'-end processing Source: GO_Central
Termination of RNA polymerase II transcription Source: Reactome

Cellular Location

Nucleus

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Anti-CSTF3 antibodies

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Mouse Anti-CSTF3 Recombinant Antibody (CBFYC-2365) (V2LY-0125-LY195)

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Target: CSTF3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat, Chicken, Cattle, Dog

Clone: CBFYC-2365

Application*: WB, IP, IF, E

Mouse Anti-CSTF3 Recombinant Antibody (1D4) (V2LY-0125-LY194)

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Target: CSTF3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1D4

Application*: E, IF, P, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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