DDT

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq]
Full Name
D-dopachrome tautomerase
Function
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
Biological Process
Melanin biosynthetic process Source: UniProtKB-KW
Negative regulation of macrophage chemotaxis Source: BHF-UCL
Positive regulation of ERK1 and ERK2 cascade Source: BHF-UCL
Positive regulation of inflammatory response Source: BHF-UCL
Positive regulation of tumor necrosis factor production Source: BHF-UCL
Cellular Location
Cytoplasm
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Anti-DDT antibodies

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Mouse Anti-DDT Recombinant Antibody (D0523) (V2LY-0425-LY26)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: D0523
Application*: E, WB, IP
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (1D5) (V2LY-0425-LY25)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D5
Application*: E, IP
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (1B1) (V2LY-0425-LY24)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B1
Application*: IH, WB
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (3A11) (V2LY-0425-LY23)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A11
Application*: WB, IF, IH
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (1H3) (V2LY-0425-LY21)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 1H3
Application*: WB, IH
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (1A1) (V2LY-0425-LY20)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 1A1
Application*: WB, IH
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (CBYCD-210) (V2LY-0425-LY19)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCD-210
Application*: WB, IF, IH
Datasheet SDS

Mouse Anti-DDT Recombinant Antibody (2H3) (CBMAB-D0517-YC)

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Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2H3
Application*: WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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