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DDT

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq]
Full Name
D-dopachrome tautomerase
Function
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
Biological Process
Melanin biosynthetic process Source: UniProtKB-KW
Negative regulation of macrophage chemotaxis Source: BHF-UCL
Positive regulation of ERK1 and ERK2 cascade Source: BHF-UCL
Positive regulation of inflammatory response Source: BHF-UCL
Positive regulation of tumor necrosis factor production Source: BHF-UCL
Cellular Location
Cytoplasm

Anti-DDT antibodies

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Target: DDT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCD-210
Application*: WB, IC, P, C, E
Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A1
Application*: P, WB
Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 1H3
Application*: WB, IH
Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2H3
Application*: WB, P
Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A11
Application*: IF, P, WB
Target: DDT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: H3
Application*: IH, WB
Target: DDT
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D5
Application*: E, IP
Target: DDT
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1G1
Application*: E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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