KLB

Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Full Name
Klotho Beta
Function
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Biological Process
Carbohydrate metabolic processIEA:InterPro
Fibroblast growth factor receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cell population proliferationIEA:Ensembl
Positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
Cellular Location
Cell membrane
Topology
Extracellular: 1-996
Helical: 997-1017
Cytoplasmic: 1018-1044
View more

Anti-KLB antibodies

+ Filters
Loading...

Mouse Anti-KLB Recombinant Antibody (885935) (CBMAB-K1024-LY)

Go to compareCompare
Target: KLB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 885935
Application*: WB
Datasheet SDS

Rabbit Anti-KLB Recombinant Antibody (1025C) (CBMAB-K0131-LY)

Go to compareCompare
Target: KLB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1025C
Application*: F, IC
Datasheet SDS

Mouse Anti-KLB Recombinant Antibody (A768) (CBMAB-AP4158LY)

Go to compareCompare
Target: KLB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: A768
Application*: ICC, IHC, IP, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry