LDHA
LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.
Full Name
LDHA
Biological Process
Glycolytic process1 PublicationNAS:UniProtKB
Lactate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Pyruvate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Substantia nigra developmentHEP:UniProtKB
Lactate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Pyruvate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Substantia nigra developmentHEP:UniProtKB
Cellular Location
Cytoplasm
Involvement in disease
Glycogen storage disease 11 (GSD11):
A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
PTM
ISGylated.
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Anti-LDHA antibodies
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CompareTarget: LDHA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: AF14A11
Application*: WB, IP
Target: LDHA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: C28H7
Application*: WB, P
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYCL-188
Application*: E, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYCL-187
Application*: E, IF, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-186
Application*: WB, IC, P, C, E
Target: LDHA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Zebrafish
Clone: CBYJL-1352
Application*: WB, P, IF, IC, IP, F
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1350
Application*: WB, P, F, IC, IF
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1349
Application*: P
Target: LDHA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: CBYJL-1347
Application*: WB, P, IF
Target: LDHA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBYJL-1346
Application*: WB, P
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: AT1A4
Application*: E, IF, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: AF9D1
Application*: WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Rabbit
Clone: CBYJL-1345
Application*: WB, IP, IC, F, E
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1344
Application*: P, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D11
Application*: P, IP, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1342
Application*: P, WB
Target: LDHA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBYJL-1341
Application*: WB, IH, IC
Target: LDHA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1340
Application*: WB, F
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 20-179
Application*: WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1339
Application*: WB, E
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJL-1338
Application*: WB, E, IC, IF
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJL-1337
Application*: IH
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBYJL-1336
Application*: E, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBYJL-1335
Application*: E
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 13F132
Application*: E, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 13F126
Application*: E, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 11C258
Application*: WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: A883
Application*: IHC, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: A882
Application*: IHC, WB
Target: LDHA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Pig
Clone: A881
Application*: ELISA, IF, IHC, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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