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MED16

MED16 (Mediator Complex Subunit 16) is a Protein Coding gene. Among its related pathways are PEDF Induced Signaling and Thyroid hormone signaling pathway. Gene Ontology (GO) annotations related to MED16 include receptor activity and transcription cofactor activity.
Full Name
Mediator Complex Subunit 16
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: UniProtKB
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Transcription by RNA polymerase II Source: ProtInc
Cellular Location
Nucleus
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Anti-MED16 antibodies

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Mouse Anti-MED16 Recombinant Antibody (3F5) (CBMAB-A9086-LY)

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Target: MED16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3F5
Application*: WB, E
Datasheet SDS

Mouse Anti-MED16 Recombinant Antibody (3B10) (CBMAB-A9085-LY)

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Target: MED16
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3B10
Application*: WB, E
Datasheet SDS

Mouse Anti-MED16 Recombinant Antibody (3A3) (CBMAB-A9084-LY)

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Target: MED16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: 3A3
Application*: WB, E
Datasheet SDS

Mouse Anti-MED16 Recombinant Antibody (2B7) (CBMAB-A9083-LY)

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Target: MED16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2B7
Application*: WB, E
Datasheet SDS

Mouse Anti-MED16 Recombinant Antibody (CBYJT-1463) (CBMAB-T0494-YJ)

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Target: MED16
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-1463
Application*: E, IC, IF, WB
Datasheet SDS

Mouse Anti-MED16 (AA 1-110) Recombinant Antibody (CBFYM-1998) (CBMAB-M2176-FY)

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Target: MED16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-1998
Application*: E, IF, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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