Neurog1
Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5-CANNTG-3). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
Full Name
neurogenin 1
Function
Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
Biological Process
Auditory behavior Source: CAFA
Cell fate commitment Source: Ensembl
Cochlea development Source: CAFA
Cochlea morphogenesis Source: CAFA
Craniofacial suture morphogenesis Source: CAFA
Genitalia development Source: CAFA
Genitalia morphogenesis Source: CAFA
Hard palate morphogenesis Source: CAFA
Inner ear development Source: CAFA
Inner ear morphogenesis Source: CAFA
Learned vocalization behavior Source: CAFA
Mastication Source: CAFA
Negative regulation of relaxation of muscle Source: CAFA
Negative regulation of saliva secretion Source: CAFA
Nervous system development Source: ProtInc
Neuromuscular process controlling balance Source: CAFA
Neuron differentiation Source: GO_Central
Peristalsis Source: CAFA
Positive regulation of DNA-binding transcription factor activity Source: UniProtKB
Positive regulation of exit from mitosis Source: Ensembl
Positive regulation of neuron differentiation Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of muscle organ development Source: CAFA
Regulation of transcription by RNA polymerase II Source: GO_Central
Thorax and anterior abdomen determination Source: CAFA
Trigeminal nerve development Source: CAFA
Vestibulocochlear nerve formation Source: CAFA
Cell fate commitment Source: Ensembl
Cochlea development Source: CAFA
Cochlea morphogenesis Source: CAFA
Craniofacial suture morphogenesis Source: CAFA
Genitalia development Source: CAFA
Genitalia morphogenesis Source: CAFA
Hard palate morphogenesis Source: CAFA
Inner ear development Source: CAFA
Inner ear morphogenesis Source: CAFA
Learned vocalization behavior Source: CAFA
Mastication Source: CAFA
Negative regulation of relaxation of muscle Source: CAFA
Negative regulation of saliva secretion Source: CAFA
Nervous system development Source: ProtInc
Neuromuscular process controlling balance Source: CAFA
Neuron differentiation Source: GO_Central
Peristalsis Source: CAFA
Positive regulation of DNA-binding transcription factor activity Source: UniProtKB
Positive regulation of exit from mitosis Source: Ensembl
Positive regulation of neuron differentiation Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of muscle organ development Source: CAFA
Regulation of transcription by RNA polymerase II Source: GO_Central
Thorax and anterior abdomen determination Source: CAFA
Trigeminal nerve development Source: CAFA
Vestibulocochlear nerve formation Source: CAFA
Cellular Location
Nucleus
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Anti-Neurog1 antibodies
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Target: NEUROG1
Sensitivity: 0.0031 ng/mL
Detection Range: 0.005-1 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Neurog1
Sensitivity: 0.009 ng/mL
Detection Range: 0.02-4 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: Neurog1
Sensitivity: 0.0099 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-0512
Application*: E, IF, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9A8
Application*: IF, IH, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: 8G8
Application*: IF, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C9
Application*: IF, IP, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5H10
Application*: IC, IH, P, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A10
Application*: IH, P, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F9
Application*: IC, IH, P, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2G4
Application*: E, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F10
Application*: E, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 15A7
Application*: IC, IH, P, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 10B10
Application*: IP, WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-1343
Application*: WB
Target: NEUROG1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4A2
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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