OSTN

OSTN is a Protein Coding gene. Diseases associated with OSTN include Acromesomelic Dysplasia. Gene Ontology annotations related to this gene include receptor binding and hormone activity.
Full Name
Osteocrin
Function
Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782).
Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782).
Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).
Biological Process
Cell differentiationIEA:UniProtKB-KW
Cell surface receptor signaling pathwayIEA:Ensembl
Endochondral bone growthIEA:Ensembl
Hormone-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of dendrite extensionManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of glucose importIEA:Ensembl
Negative regulation of osteoblast differentiationIEA:Ensembl
Cellular Location
Secreted
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Anti-OSTN antibodies

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Mouse Anti-OSTN Recombinant Antibody (CBFYM-3042) (CBMAB-M3238-FY)

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Target: OSTN
Host: Mouse
Specificity: Human
Clone: CBFYM-3042
Application*: WB, IP, IF, E
Datasheet SDS

Rat Anti-OSTN Recombinant Antibody (CBXO-0248) (CBMAB-O0661-CQ)

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Target: OSTN
Host: Rat
Specificity: Mouse
Clone: CBXO-0248
Application*: IP, WB
Datasheet SDS

Rat Anti-OSTN (AA 28-130) Recombinant Antibody (CBXO-0379) (CBMAB-O0660-CQ)

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Target: OSTN
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBXO-0379
Application*: WB
Datasheet SDS

Rat Anti-OSTN (AA 28-130) Recombinant Antibody (311417) (CBMAB-O0659-CQ)

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Target: OSTN
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 311417
Application*: IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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