RPS14

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

Ribosomal Protein S14

Biological Process

Biological Process cytoplasmic translation1 PublicationIC:FlyBase
Biological Process erythrocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process maturation of SSU-rRNAISS:UniProtKB
Biological Process maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ribosomal small subunit assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process translationManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

cytoplasm
cytosol
cytosolic ribosome
cytosolic small ribosomal subunit
extracellular exosome
focal adhesion
membrane
nucleolus
nucleoplasm
postsynaptic density