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RTRAF

RTRAF (RNA Transcription, Translation And Transport Factor) is a Protein Coding gene. Diseases associated with RTRAF include Influenza and Leukoencephalopathy With Vanishing White Matter. Among its related pathways are Gene Expression and tRNA processing.
Full Name
RNA Transcription, Translation And Transport Factor
Function
RNA-binding protein involved in modulation of mRNA transcription by Polymerase II (PubMed:16950395).
Component of the tRNA-splicing ligase complex and is required for tRNA ligation (PubMed:24870230).
May be required for RNA transport (PubMed:24608264).
(Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication (PubMed:21900157).
Biological Process
Biological Process negative regulation of protein kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process RNA transportManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process tRNA splicing, via endonucleolytic cleavage and ligationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Cytoplasm, cytosol
Cytoplasm, perinuclear region
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
May localize at the centrosome during mitosis (PubMed:15147888).
Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264).
Nucleus
Cytoplasm
(Microbial infection) Following influenza A virus (IAV) infection, included in influenza A virions via its association with packaged viral ribonucleoproteins (vRNP) in the nucleus and cytoplasm (PubMed:21900157, PubMed:26864902).

Anti-RTRAF antibodies

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Mouse Anti-RTRAF Recombinant Antibody (2A4) (CBMAB-C4615-LY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A4
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (2B5) (CBMAB-C4704-LY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2B5
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (2D2) (CBMAB-C4879-LY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D2
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (2D6) (CBMAB-C4915-LY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D6
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (CBFYC-3084) (CBMAB-C3161-FY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3084
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (CBYY-C2101) (CBMAB-C3539-YY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2101
Application*: P, WB

Mouse Anti-RTRAF Recombinant Antibody (CBYY-C2103) (CBMAB-C3541-YY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C2103
Application*: P, WB

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4384) (CBMAB-C5765WJ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4384
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4385) (CBMAB-C5766WJ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-4385
Application*: WB

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4388) (CBMAB-C5769WJ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4388
Application*: WB, IH

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4390) (CBMAB-C5771WJ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-4390
Application*: WB, IH

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4391) (CBMAB-C5772WJ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4391
Application*: IH

Mouse Anti-RTRAF Recombinant Antibody (UMAB182) (CBMAB-C12363-LY)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: UMAB182
Application*: P

Mouse Anti-RTRAF Recombinant Antibody (CBXC-2479) (CBMAB-C5895-CQ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2479
Application*: WB, IH

Mouse Anti-RTRAF Recombinant Antibody (CBXC-2671) (CBMAB-C5896-CQ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2671
Application*: WB, IH

Mouse Anti-RTRAF Recombinant Antibody (CBXC-2333) (CBMAB-C5897-CQ)

Datasheet SDS
Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2333
Application*: IH

Rabbit Anti-RTRAF Recombinant Antibody (EPR15799) (CBMAB-1786-CN)

Datasheet SDS
Target: RTRAF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR15799
Application*: IF, IP, WB, P
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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