RTRAF

RTRAF (RNA Transcription, Translation And Transport Factor) is a Protein Coding gene. Diseases associated with RTRAF include Influenza and Leukoencephalopathy With Vanishing White Matter. Among its related pathways are Gene Expression and tRNA processing.
Full Name
RNA Transcription, Translation And Transport Factor
Function
RNA-binding protein involved in modulation of mRNA transcription by Polymerase II (PubMed:16950395).
Component of the tRNA-splicing ligase complex and is required for tRNA ligation (PubMed:24870230).
May be required for RNA transport (PubMed:24608264).
(Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication (PubMed:21900157).
Biological Process
Biological Process negative regulation of protein kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process RNA transportManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process tRNA splicing, via endonucleolytic cleavage and ligationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Cytoplasm, cytosol
Cytoplasm, perinuclear region
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
May localize at the centrosome during mitosis (PubMed:15147888).
Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264).
Nucleus
Cytoplasm
(Microbial infection) Following influenza A virus (IAV) infection, included in influenza A virions via its association with packaged viral ribonucleoproteins (vRNP) in the nucleus and cytoplasm (PubMed:21900157, PubMed:26864902).
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Anti-RTRAF antibodies

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Mouse Anti-RTRAF Recombinant Antibody (UMAB182) (CBMAB-C12363-LY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: UMAB182
Application*: P
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4391) (CBMAB-C5772WJ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4391
Application*: IH
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4390) (CBMAB-C5771WJ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-4390
Application*: WB, IH
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4388) (CBMAB-C5769WJ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4388
Application*: WB, IH
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4385) (CBMAB-C5766WJ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-4385
Application*: WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBWJC-4384) (CBMAB-C5765WJ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4384
Application*: WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBXC-2333) (CBMAB-C5897-CQ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2333
Application*: IH
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBXC-2671) (CBMAB-C5896-CQ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2671
Application*: WB, IH
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBXC-2479) (CBMAB-C5895-CQ)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2479
Application*: WB, IH
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBYY-C2103) (CBMAB-C3541-YY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C2103
Application*: P, WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBYY-C2101) (CBMAB-C3539-YY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2101
Application*: P, WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (CBFYC-3084) (CBMAB-C3161-FY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3084
Application*: WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (2D6) (CBMAB-C4915-LY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D6
Application*: WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (2D2) (CBMAB-C4879-LY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D2
Application*: WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (2B5) (CBMAB-C4704-LY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2B5
Application*: WB
Datasheet SDS

Mouse Anti-RTRAF Recombinant Antibody (2A4) (CBMAB-C4615-LY)

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Target: RTRAF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A4
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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