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SPP1

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Anti-SPP1 antibodies

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Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-O0490-CQ Rabbit Anti-SPP1 (AA 158-165) Recombinant Antibody (CBXO-0503) SPP1 Rabbit IgG Human, Mouse, Rat CBXO-0503 F, IC, IF, WB
CBMAB-O0879-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0236) SPP1 Mouse IgG1, κ Human CBXO-0236 E, WB
CBMAB-O0878-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0235) SPP1 Mouse IgG1, κ Human CBXO-0235 E, WB
CBMAB-O0877-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0221) SPP1 Mouse IgG1 Human, Mouse CBXO-0221 E, WB
CBMAB-O0876-CQ Mouse Anti-SPP1 Recombinant Antibody (53) SPP1 Mouse IgG2a Human 53 WB, E, IH, P
CBMAB-O0875-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0191) SPP1 Mouse IgG2a Human CBXO-0191 E, WB, P
CBMAB-O0874-CQ Mouse Anti-SPP1 Recombinant Antibody (2A1) SPP1 Mouse IgG1, κ Human, Mouse 2A1 WB, E, IP, IF, IH
CBMAB-O0873-CQ Mouse Anti-SPP1 Recombinant Antibody (1H3) SPP1 Mouse IgG1, κ Human, Mouse 1H3 WB, E, IP, B
CBMAB-O0872-CQ Mouse Anti-SPP1 Recombinant Antibody (3D9) SPP1 Mouse IgG1, κ Human, Mouse 3D9 WB, E, IP
CBMAB-O0871-CQ Mouse Anti-SPP1 Recombinant Antibody (10F6) SPP1 Mouse IgG1, κ Human, Mouse 10F6 WB, E, IP
CBMAB-O0870-CQ Mouse Anti-SPP1 Recombinant Antibody (1G4) SPP1 Mouse IgG2a, κ Human 1G4 WB, E, IP, IH
CBMAB-O0869-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0505) SPP1 Mouse IgG2a Human CBXO-0505 E, IH, WB
CBMAB-O0868-CQ Mouse Anti-SPP1 Recombinant Antibody (2E11) SPP1 Mouse IgG1, κ Human 2E11 E, WB
CBMAB-O0867-CQ Mouse Anti-SPP1 Recombinant Antibody (X1) SPP1 Mouse IgG2b, κ Human X1 E, IH, WB
CBMAB-O0866-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0222) SPP1 Mouse IgG2a Human CBXO-0222 F
CBMAB-O0865-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0220) SPP1 Mouse IgG1 Human, Mouse CBXO-0220 E, WB
CBMAB-O0864-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0117) SPP1 Mouse IgG Human CBXO-0117 E, WB, P, IF
CBMAB-O0863-CQ Mouse Anti-SPP1 Recombinant Antibody (20Z7) SPP1 Mouse IgG2 Human 20Z7 WB
CBMAB-O0862-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0498) SPP1 Mouse IgG2b, κ Human, Mouse CBXO-0498 WB, IF
CBMAB-O0861-CQ Mouse Anti-SPP1 Recombinant Antibody (14C08) SPP1 Mouse IgG1, κ Human 14C08 SE
CBMAB-O0860-CQ Mouse Anti-SPP1 Recombinant Antibody (M574) SPP1 Mouse IgG1 Human, Rat, Mouse M574 WB, E, IC
CBMAB-O0859-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0477) SPP1 Mouse IgG2a Human CBXO-0477 F
CBMAB-O0858-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0116) SPP1 Mouse IgG2b, κ Human CBXO-0116 E, WB, P
CBMAB-O0857-CQ Mouse Anti-SPP1 (AA 17-314) Recombinant Antibody (5E4) SPP1 Mouse IgG1 Human 5E4 WB, IH
CBMAB-O0856-CQ Mouse Anti-SPP1 (AA 17-300) Recombinant Antibody (CBXO-0368) SPP1 Mouse IgG2b Human CBXO-0368 IH
CBMAB-O0855-CQ Mouse Anti-SPP1 (AA 167-314) Recombinant Antibody (7C5H12) SPP1 Mouse IgG1 Human 7C5H12 IC, IF, IH, WB
CBMAB-O0854-CQ Mouse Anti-SPP1 (AA 1-301) Recombinant Antibody (4H7) SPP1 Mouse IgG2a, κ Human, Mouse 4H7 E, WB
CBMAB-O0014-CQ Mouse Anti-SPP1 Recombinant Antibody (1B20) SPP1 Mouse IgG1 Human, Rat, Rabbit 1B20 WB, IH, IF, IP, P, C
CBMAB-O0002-CQ Mouse Anti-SPP1 (AA 17-300) Recombinant Antibody (CBXO-0213) SPP1 Mouse IgG2a Human CBXO-0213 F
CBMAB-O0489-CQ Rabbit Anti-SPP1 (AA 158-165) Recombinant Antibody (CBXO-0502) SPP1 Rabbit IgG Human, Mouse CBXO-0502 F, IC, IF, WB
CBMAB-O0486-CQ Rabbit Anti-SPP1 Recombinant Antibody (CBXO-0189) SPP1 Rabbit IgG Human CBXO-0189 WB, E, F, IP
CBMAB-O0485-CQ Rabbit Anti-SPP1 Recombinant Antibody (CBXO-0171) SPP1 Rabbit IgG Human CBXO-0171 E
CBMAB-0878-YC Mouse Anti-SPP1 Recombinant Antibody (MPIIIB10(1)) SPP1 Mouse IgG1 Rat, Human, Rabbit, Mouse MPIIIB10(1) IF, IF-cells, IH
CBMAB-O0109-CQ Mouse Anti-SPP1 Recombinant Antibody (2C5) SPP1 Mouse IgG1, κ Human, Mouse 2C5 WB, E, IP, IH, B
CBMAB-O0108-CQ Mouse Anti-SPP1 Recombinant Antibody (2H9) SPP1 Mouse IgG1, κ Human 2H9 E, WB
CBMAB-O0107-CQ Mouse Anti-SPP1 Recombinant Antibody (1F11) SPP1 Mouse IgG1, κ Human 1F11 E, WB
CBMAB-O0103-CQ Mouse Anti-SPP1 (AA 17-300) Recombinant Antibody (CBXO-0371) SPP1 Mouse IgG2a Human CBXO-0371 WB
CBMAB-O0094-CQ Rabbit Anti-SPP1 Recombinant Antibody (CBXO-0141) SPP1 Rabbit IgG Mouse, Human CBXO-0141 WB, F, IF
CBMAB-S2683-CQ Rabbit Anti-SPP1 Recombinant Antibody (CBXS-5473) SPP1 Rabbit IgG Mouse, Human CBXS-5473 F, IC, IH, WB
CBMAB-S1817-CQ Mouse Anti-SPP1 (AA 17-314) Recombinant Antibody (CBXS-4577) SPP1 Mouse IgG1 Human CBXS-4577 P, WB
CBMAB-S1810-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-4570) SPP1 Mouse IgG1, κ Human CBXS-4570 E, WB
CBMAB-A8563-LY Mouse Anti-SPP1 Recombinant Antibody (4G12) SPP1 Mouse IgG1, κ Human 4G12 WB, E
CBMAB-A8562-LY Mouse Anti-SPP1 Recombinant Antibody (4F2) SPP1 Mouse IgG1, κ Human 4F2 WB, E
CBMAB-A8561-LY Mouse Anti-SPP1 Recombinant Antibody (4D8) SPP1 Mouse IgG1, κ Human 4D8 WB, E
CBMAB-R4269-CN Mouse Anti-SPP1 Recombinant Antibody (1B2C2) SPP1 Mouse IgG2a Human 1B2C2 E, WB, IH
CBMAB-S1936-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-4705) SPP1 Mouse IgG1 Human CBXS-4705 WB
CBMAB-S1900-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-4661) SPP1 Mouse IgG1, κ Human CBXS-4661 E, WB
CBMAB-S0968-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-3693) SPP1 Mouse IgG2a Human CBXS-3693 F
CBMAB-S2426-CQ Mouse Anti-SPP1 (AA 17-314) Recombinant Antibody (CBXS-5209) SPP1 Mouse IgG1 Human CBXS-5209 WB
CBMAB-S2381-CQ Mouse Anti-SPP1 (AA 17-314) Recombinant Antibody (CBXS-5163) SPP1 Mouse IgG1 Human CBXS-5163 P, WB
CBMAB-A8560-LY Mouse Anti-SPP1 Recombinant Antibody (4C4) SPP1 Mouse IgG2a, κ Human 4C4 WB, E
CBMAB-A8559-LY Mouse Anti-SPP1 Recombinant Antibody (4B8) SPP1 Mouse IgG2b, κ Human 4B8 WB, E
CBMAB-A8558-LY Mouse Anti-SPP1 Recombinant Antibody (4B2) SPP1 Mouse IgG2b, κ Human 4B2 WB, E
CBMAB-A8557-LY Mouse Anti-SPP1 Recombinant Antibody (3G6) SPP1 Mouse IgG2a, κ Human 3G6 WB, E
CBMAB-A8556-LY Mouse Anti-SPP1 Recombinant Antibody (3C7) SPP1 Mouse IgG2b, κ Human 3C7 WB, E
CBMAB-A8555-LY Mouse Anti-SPP1 Recombinant Antibody (3B11) SPP1 Mouse IgG2b, κ Human, Mouse 3B11 WB, E
CBMAB-A8554-LY Mouse Anti-SPP1 Recombinant Antibody (2D12) SPP1 Mouse IgG2a, κ Human, Mouse 2D12 WB, E
CBMAB-A8553-LY Mouse Anti-SPP1 Recombinant Antibody (1F5) SPP1 Mouse IgG2a, κ Human, Mouse 1F5 WB, E
CBMAB-A8552-LY Mouse Anti-SPP1 Recombinant Antibody (1D7) SPP1 Mouse IgG2a, κ Human, Mouse 1D7 WB, E
CBMAB-A8551-LY Mouse Anti-SPP1 Recombinant Antibody (1D4) SPP1 Mouse IgG2a, κ Human, Mouse 1D4 WB, E
CBMAB-A8550-LY Mouse Anti-SPP1 Recombinant Antibody (1A7) SPP1 Mouse IgG2a, κ Human, Mouse 1A7 WB, E
CBMAB-A8549-LY Mouse Anti-SPP1 Recombinant Antibody (3E11) SPP1 Mouse IgG2a, κ Human 3E11 WB, E
CBMAB-A8548-LY Mouse Anti-SPP1 Recombinant Antibody (1E10) SPP1 Mouse IgG2a, κ Human 1E10 WB, E
CBMAB-A8547-LY Mouse Anti-SPP1 Recombinant Antibody (4E6) SPP1 Mouse IgG1, κ Human 4E6 WB, E
CBMAB-A8546-LY Mouse Anti-SPP1 Recombinant Antibody (1E6) SPP1 Mouse IgG2a, κ Human 1E6 WB, E
CBMAB-S6465-CQ Mouse Anti-SPP1 (C-Term) Recombinant Antibody (CBXS-6179) SPP1 Mouse IgG1 Human CBXS-6179 IH
CBMAB-S1689-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-4447) SPP1 Mouse IgG1, κ Human CBXS-4447 E, WB
CBMAB-S0722-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-5870) SPP1 Mouse IgG1 Human CBXS-5870 E, IC, P, WB
CBMAB-S0647-CQ Mouse Anti-SPP1 (AA 17-314) Recombinant Antibody (CBXS-5789) SPP1 Mouse IgG1 Human CBXS-5789 WB
CBMAB-O0880-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXO-0245) SPP1 Mouse IgG2 Human CBXO-0245 WB
CBMAB-S2030-CQ Mouse Anti-SPP1 (AA 17-314) Recombinant Antibody (CBXS-4804) SPP1 Mouse IgG2b Human CBXS-4804 WB
CBMAB-S0999-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-3724) SPP1 Mouse IgG1, κ Human CBXS-3724 E
CBMAB-S0584-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-5717) SPP1 Mouse IgG2a, κ Human CBXS-5717 WB
CBMAB-S1762-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-4522) SPP1 Mouse IgG1, κ Human CBXS-4522 E, WB
CBMAB-S1358-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-4101) SPP1 Mouse IgG1, κ Human CBXS-4101 E, WB
CBMAB-S0760-CQ Mouse Anti-SPP1 (C-Term) Recombinant Antibody (CBXS-5911) SPP1 Mouse IgG2a, κ Human CBXS-5911 WB
CBMAB-S0224-CQ Mouse Anti-SPP1 (C-Term) Recombinant Antibody (CBXS-3866) SPP1 Mouse IgG1 Human CBXS-3866 IC, P, IP, WB
CBMAB-O0110-CQ Mouse Anti-SPP1 Recombinant Antibody (2F10) SPP1 Mouse IgG1, κ Human 2F10 IC, IF, P, WB
CBMAB-S0942-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-3663) SPP1 Mouse IgG2a Human CBXS-3663 F
CBMAB-S0887-CQ Mouse Anti-SPP1 Recombinant Antibody (CBXS-3601) SPP1 Mouse IgG Human CBXS-3601 IH, WB
PEP-182861CQ Mouse SPP1 Peptide (RGDSLAYG) SPP1
PEP-182860CQ Mouse SPP1 Peptide (PTVDVPNGRGDS) SPP1
PEP-182859CQ Mouse SPP1 Peptide (LAYGLR) SPP1
PEP-182858CQ Mouse SPP1 Peptide (GDSLAYG) SPP1
PEP-182857CQ Mouse SPP1 Peptide (VDVPNGRGDSLAYGLRS) SPP1
PEP-182856CQ Mouse SPP1 Peptide (SLAYGLR) SPP1
PEP-110891CQ Human SPP1 Peptide (SSEEKQLYNKY) SPP1
PEP-110890CQ Human SPP1 Peptide (GAYKAIPVAQDL) SPP1
PEP-054682CQ Human SPP1 Peptide (GRGDSVVYGLR) SPP1
PEP-054681CQ Human SPP1 Peptide (VATWLNPDPSQK) SPP1
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)