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ST13

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Full Name
ST13, Hsp70 Interacting Protein
Function
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity).
Biological Process
Biological Process chaperone cofactor-dependent protein refoldingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein foldingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process response to bacteriumIEA:Ensembl
Cellular Location
Cytoplasm

Anti-ST13 antibodies

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Target: ST13
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B2
Application*: WB, E
Target: ST13
Host: Mouse
Specificity: Human
Clone: CBXS-2649
Application*: E, IH, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBXS-2471
Application*: E, IH, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-0743
Application*: SE, E, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0742
Application*: IP, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0741
Application*: E, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-6121
Application*: E, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-6108
Application*: E, WB, IH
Target: ST13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5488
Application*: E, IF, IH, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4758
Application*: E, P, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4384
Application*: E, WB
Target: ST13
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBFYH-2785
Application*: WB, P, IC, F
Target: ST13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AT1F1
Application*: E, IH, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat, Monkey
Clone: CBFYH-3310
Application*: WB, IP
Target: ST13
Host: Mouse
Antibody Isotype: IgG
Specificity: Chicken, Human, Mouse, Rabbit
Clone: CBFYH-2783
Application*: F, IC, IF, IP, WB
Target: ST13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-2784
Application*: WB, E, IH, P
Target: ST13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 3B10
Application*: WB, IF, IHC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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