Mouse Anti-ACTA2 Recombinant Antibody (V2-3360) (CBMAB-0077-CN)
Compare
Online Inquiry
Basic Information
| Application | Note |
| WB | 1:5,000-1:50,000 |
| IHC | 1:1,000-1:2,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
| Human | P62736 |
| Mouse | P62737 |
| Chicken | P08023 |
| Monkey | A0A0D9R387 |
| Dog | F2Z4N0 |
| Shark | A0A4W3JU30 |
Mesenchyme migration
Muscle contraction
Positive regulation of gene expression
Positive regulation of transcription, DNA-templated
Regulation of blood pressure
Response to virus
Vascular associated smooth muscle contraction
Moyamoya disease 5 (MYMY5): A progressive cerebral angiopathy characterized by bilateral intracranial carotid artery stenosis and telangiectatic vessels in the region of the basal ganglia. The abnormal vessels resemble a 'puff of smoke' (moyamoya) on cerebral angiogram. Affected individuals can develop transient ischemic attacks and/or cerebral infarction, and rupture of the collateral vessels can cause intracranial hemorrhage. Hemiplegia of sudden onset and epileptic seizures constitute the prevailing presentation in childhood, while subarachnoid bleeding occurs more frequently in adults.
Multisystemic smooth muscle dysfunction syndrome (MSMDS): A syndrome characterized by dysfunction of smooth muscle cells throughout the body, leading to aortic and cerebrovascular disease, fixed dilated pupils, hypotonic bladder, malrotation, and hypoperistalsis of the gut and pulmonary hypertension.
Monomethylation at Lys-86 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
Methylated at His-75 by SETD3.
(Microbial infection) Monomeric actin is cross-linked by V.cholerae toxins RtxA and VgrG1 in case of infection: bacterial toxins mediate the cross-link between Lys-52 of one monomer and Glu-272 of another actin monomer, resulting in formation of highly toxic actin oligomers that cause cell rounding. The toxin can be highly efficient at very low concentrations by acting on formin homology family proteins: toxic actin oligomers bind with high affinity to formins and adversely affect both nucleation and elongation abilities of formins, causing their potent inhibition in both profilin-dependent and independent manners.
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Antibody Pairs
ACTA2 Matched Antibody Pair (008) (CAT#: APMAB-008LY)
Related Products
Mouse Anti-ACTA2 Recombinant Antibody (CBT133) (CAT#: V2LY-0625-LY3776)
Mouse Anti-ACTA2 Recombinant Antibody (CBT3832) (CAT#: V2LY-0625-LY1379)
ACTA2 Matched Antibody Pair (008) (CAT#: APMAB-008LY)
Mouse Anti-ACTA2 Recombinant Antibody (CBT3994) (CAT#: V2LY-0625-LY2568)
Mouse Anti-ACTA2 Recombinant Antibody (EC6) (CAT#: V2LY-0624-LY6)
Mouse Anti-ACTA2 Recombinant Antibody (V2-365986) (CAT#: CBMAB-S2933-CQ)
Mouse Anti-ACTA2 Recombinant Antibody (CBT1308) (CAT#: V2LY-0625-LY2874)
Mouse Anti-ACTA2 Recombinant Antibody (V2-179502) (CAT#: CBMAB-A0819-YC)
Rabbit Anti-ACTA2 Recombinant Antibody (V2-179523) (CAT#: CBMAB-A0840-YC)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
