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Mouse Anti-DHX16 Recombinant Antibody (D0847) (V2LY-0425-LY286)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
D0847
Antibody Isotype
IgG1
Application
WB, IP, IF

Basic Information

Immunogen
Amino acids 256-366 of human DDX16.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Gelatin & PBS
Preservative
Sodium Azide
Concentration
0.1 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DEAH (Asp-Glu-Ala-His) box polypeptide 16
Entrez Gene ID
8449
UniProt ID
O60231
Function
Required for pre-mRNA splicing as component of the spliceosome (PubMed:20423332, PubMed:20841358, PubMed:25296192, PubMed:29360106).

Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction.
Biological Process
mRNA splicing, via spliceosome Source: UniProtKB
RNA splicing Source: ProtInc
Cellular Location
Nucleus; Nucleoplasm
Involvement in disease
Neuromuscular oculoauditory syndrome (NMOAS):
An autosomal dominant neuromuscular disorder characterized by variable features including myopathy, neuropathy, hypotonia, joint contractures, growth delay, chorioretinal lacunae, sensorineuronal deafness, agenesis of the corpus callosum, and seizures.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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