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Mouse Anti-DUSP27 Recombinant Antibody (1F3) (CBMAB-D1891-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dual Specificity Phosphatase 27, Atypical (DUSP27). The antibody can be used for immunoassay techniques, such as WB, FC.
See all DUSP27 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F3
Antibody Isotype
IgG1
Application
WB, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Dual Specificity Phosphatase 27, Atypical
Introduction
DUSP27 (Dual Specificity Phosphatase 27, Atypical) is a protein coding gene. It has proved that the protein has phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. And a paralog is DUPD1.
Entrez Gene ID
92235
UniProt ID
Q5VZP5
Alternative Names
Dual Specificity Phosphatase 27, Atypical; Dual Specificity Phosphatase 27 (Putative);
Research Area
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (PubMed:17498703).

Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (By similarity).

Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity).
Biological Process
Glucose homeostasis Source: Ensembl
Muscle cell differentiation Source: UniProtKB
Negative regulation of ERK1 and ERK2 cascade Source: UniProtKB
Protein dephosphorylation Source: UniProtKB
Cellular Location
Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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