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Mouse Anti-FBXO8 (AA 1-78) Recombinant Antibody (CBXF-0421) (CBMAB-F0366-CQ)

This product is a mouse antibody that recognizes FBXO8 (AA 1-78). The antibody CBXF-0421 can be used for immunoassay techniques such as: ELISA, WB.
See all FBXO8 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0421
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-78

Target

Full Name
F-box protein 8
Introduction
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Entrez Gene ID
26269
UniProt ID
Q9NRD0
Alternative Names
F-Box Protein 8; F-Box/SEC7 Protein FBS; F-Box Only Protein 8; FBX8; FBS; F-Box Protein Fbx8; DC10;
Research Area
May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).
Biological Process
Regulation of ARF protein signal transduction Source: InterPro
Ubiquitin-dependent protein catabolic process Source: UniProtKB
Cellular Location
Ubiquitin ligase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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